Transcriptional regulation of cholesterol 24-hydroxylase by histone deacetylase inhibitors
نویسندگان
چکیده
منابع مشابه
Transcriptional regulation of cholesterol 24-hydroxylase by histone deacetylase inhibitors.
The mechanistic basis for the tissue specific expression of cholesterol elimination pathways is poorly understood. To gain additional insight into this phenomenon we considered it of interest to investigate if epigenetic mechanisms are involved in the regulation of the brain-specific enzyme cholesterol 24-hydroxylase (CYP46A1), a key regulator of brain cholesterol elimination. We demonstrated a...
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ژورنال
عنوان ژورنال: Biochemical and Biophysical Research Communications
سال: 2009
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2008.11.103